Encore 5 being a 32 bits application, it won’t run in any recent version of macOS. Mojave (macOS 10.14.6) being the latest possible option (Encore being the reason why I’m still using Mojave!) Encore 6 should run on a Mac running Ventura, I suppose, but we’re still hoping to see it come to live. 😉
Actually, Encore 5.0.7 for Mac works much better over MacOS 10.14 Mojave than it ever did over Sierra and High Sierra. Unfortunately, E5, being 32 bit only cannot work over Catalina and later, as they require 64 bit apps.